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OD36

Product Specifications

CAS Number

1638644-62-8

Target

ALK, TGF-beta/Smad, RIP kinase

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors, Stem Cells, Apoptosis, NF-κB

Purity

0.9989

Bioactivity

OD36 is a selective and potent RIPK2 inhibitor with an IC50 of 5.3 nM.OD36 inhibits ALK2 signaling and osteogenic differentiation (KD: 37 nM), and binds efficiently to the ALK2 kinase ATP pocket.

Smiles

Clc1cc2OCCOCCN=C3Nc4c(cnn4C=C3)-c(c1)c2

Molecular Formula

C16H15ClN4O2

Molecular Weight

330.77

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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