Miro1 Reducer
Product Specifications
CAS Number
2624336-91-8
Target
Others
Related Pathways
Others
Bioactivity
Promotes proteasomal degradation of Miro1 (mitochondrial Rho GTPase 1) . Reduces Miro1 levels in fibroblasts from Parkinson's disease (PD) patients (IC50 = 7.8 μM) . Exhibits no significant effect on related outer mitochondrial membrane protein Mitofusin. Reduces stress-induced degeneration of dopaminergic neurons derived from PD patient iPSCs. Rescues age-dependent neuronal loss and prolongs lifespan in fly PD models.
Smiles
Cl.O=C(NC1=CC=C(C=C1)NC2=NC=NC(=C2)N3C=NC=C3)NC=4C=CC=C(F)C4
Molecular Formula
C20H17FN7OCl
Molecular Weight
425.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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