Mitoguazone
Product Specifications
CAS Number
459-86-9
Target
Apoptosis, HIV Protease
Related Pathways
Apoptosis, Microbiology/Virology, Proteases/Proteasome
Purity
0.98
Bioactivity
Mitoguazone (Methyl-GAG) is a selective S-adenosyl-methionine decarboxylase inhibitor that penetrates the blood-brain barrier and disrupts polyamine biosynthesis. Mitoguazone is a synthetic polycarbonyl derivative with anti-tumor activity that inhibits the integration of HIV DNA into cellular DNA in monocytes and macrophages, inducing apoptosis. Mitoguazone can be used to prevent acute leukemia, Hodgkin lymphoma and non-Hodgkin lymphoma.
Smiles
C\C(\C=N\NC(N)=N)=N/NC(N)=N
Molecular Formula
C5H12N8
Molecular Weight
184.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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