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MS351

Product Specifications

CAS Number

472984-79-5

Target

Others

Related Pathways

Others

Bioactivity

MS351 is an antagonist of chromobox 7 (CBX7) that acts by binding the CBX7 chromodomain. It enhances the binding of long noncoding RNA to the CBX7 chromodomain when used at 25 μM. MS351 induces transcriptional derepression of CBX7 target genes, including p16 (INK4a), in mouse embryonic stem cells and human prostate cancer PC3 cells.

Smiles

Cl.ClC1=CC=C(C=C1Cl)C(O)CN2C=3C=CC=CC3N(C2=N)CC=4C=CC=CC4C

Molecular Formula

C23H22Cl3N3O

Molecular Weight

462.8

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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