MS351
Product Specifications
CAS Number
472984-79-5
Target
Others
Related Pathways
Others
Bioactivity
MS351 is an antagonist of chromobox 7 (CBX7) that acts by binding the CBX7 chromodomain. It enhances the binding of long noncoding RNA to the CBX7 chromodomain when used at 25 μM. MS351 induces transcriptional derepression of CBX7 target genes, including p16 (INK4a), in mouse embryonic stem cells and human prostate cancer PC3 cells.
Smiles
Cl.ClC1=CC=C(C=C1Cl)C(O)CN2C=3C=CC=CC3N(C2=N)CC=4C=CC=CC4C
Molecular Formula
C23H22Cl3N3O
Molecular Weight
462.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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