SAR502250
Product Specifications
CAS Number
503860-57-9
Target
GSK-3, Others
Related Pathways
Others, PI3K/Akt/mTOR signaling, Stem Cells
Bioactivity
SAR502250 is a potent, selective, ATP-competitive, orally active, and brain-penetrant GSK3 inhibitor with a human GSK-3β IC50 value of 12 nM, exhibiting antidepressant-like activity and being researched for potential application in Alzheimer's disease (AD) treatment.
Smiles
Cn1c(nc(cc1=O)-c1ccncn1)N1CCO[C@H](C1)c1ccc(F)cc1
Molecular Formula
C19H18FN5O2
Molecular Weight
367.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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