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GSK-3β inhibitor 8

Product Specifications

CAS Number

1139875-74-3

Target

GSK-3, Wnt/beta-catenin

Related Pathways

Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Stem Cells

Purity

0.9846

Bioactivity

GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent and selective GSK-3β inhibitor with an IC50 value of 64 nM.GSK-3β inhibitor 8 is a thienopyrimidine derivative that negatively regulates the Wnt signaling pathway and stimulates β-cell proliferation.

Smiles

C(=O)(C1=C(Cl)C=C(NC=2N=C(C=CN2)C3=CC=CS3)C=C1)N4CCN(C)CC4

Molecular Formula

C20H20ClN5OS

Molecular Weight

413.92

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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