GSK-3β inhibitor 8
Product Specifications
CAS Number
1139875-74-3
Target
GSK-3, Wnt/beta-catenin
Related Pathways
Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Stem Cells
Purity
0.9846
Bioactivity
GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent and selective GSK-3β inhibitor with an IC50 value of 64 nM.GSK-3β inhibitor 8 is a thienopyrimidine derivative that negatively regulates the Wnt signaling pathway and stimulates β-cell proliferation.
Smiles
C(=O)(C1=C(Cl)C=C(NC=2N=C(C=CN2)C3=CC=CS3)C=C1)N4CCN(C)CC4
Molecular Formula
C20H20ClN5OS
Molecular Weight
413.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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