(2R,4R) -APDC (hydrate)
(2R,4R) -APDC hydrate ((2R,4R) -4-Aminopyrrolidine-2,4-dicarboxylic acid hydrate) is a group II metabotropic glutamate receptor (mGluR) agonist. (2R,4R) -APDC hydrate affects cell proliferation by inhibiting glutamate release, enhancing motor responses produced by D1 receptor activation, or reducing brain-derived neurotrophic factor (BDNF) levels. (2R,4R) -APDC hydrate can be used in the study of epilepsy and other neurological diseases[1].
Product Specifications
Product Name Alternative
(2R,4R) -4-Aminopyrrolidine-2,4-dicarboxylic acid (hydrate)
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/2r-4r-apdc-hydrate.html
Purity
98.0
Solubility
H2O : 20 mg/mL (ultrasonic;warming)
Smiles
O=C([C@@H]1NC[C@](C(O)=O)(N)C1)O.O
Molecular Formula
C6H12N2O5
Molecular Weight
192.17
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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