(2R,4R) -APDC (hydrate)

(2R,4R) -APDC hydrate ((2R,4R) -4-Aminopyrrolidine-2,4-dicarboxylic acid hydrate) is a group II metabotropic glutamate receptor (mGluR) agonist. (2R,4R) -APDC hydrate affects cell proliferation by inhibiting glutamate release, enhancing motor responses produced by D1 receptor activation, or reducing brain-derived neurotrophic factor (BDNF) levels. (2R,4R) -APDC hydrate can be used in the study of epilepsy and other neurological diseases[1].