(±) 17-HETE
Product Specifications
CAS Number
128914-47-6
Target
Others, ATPase, Cytochromes P450
Related Pathways
Metabolism, Membrane transporter/Ion channel, Others
Bioactivity
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±) 17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. At a concentration of 2 μM the (S) -enantiomer of 17-HETE inhibits proximal tubule ATPase activity by as much as 70%, whereas the (R) -isomer is inactive.
Smiles
CCCC(O)C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
Molecular Formula
C20H32O3
Molecular Weight
320.473
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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