4-deoxy Nivalenol-13C15

4-deoxy Nivalenol-13C15is intended for use as an internal standard for the quantification of 4-deoxy nivalenol by GC- or LC-MS. 4-deoxy Nivalenol is a trichothecene mycotoxin that has been found inFusarium.1It binds to eukaryotic ribosomes and inhibits protein synthesis in mice when administered at doses ranging from 5 to 25 mg/kg. 4-deoxy Nivalenol (0.1 and 0.2 mg/kg) induces emesis in pigs and decreases feed consumption in pigs when administered at a dose of 40 ppb in the diet.2It induces lethality in mice (LD50= 46-78 mg/kg) .34-deoxy Nivalenol has been found inF. graminearum-infected cereal grains such as wheat, barley, and corn.

[H][13C@@]12O[13C@]3([H])[13CH]=[13C]([13CH3])[13C](=O)[13C@@H](O)[13C@]3([13CH2]O)[13C@@]([13CH3])([13CH2][13C@H]1O)[13C@]21[13CH2]O1 |t:5,TLB:22:20:2.3.12:18.17,THB:13:12:20:18.17,10:12:20:18.17,19:18:20:2.3.12,21:20:2.3.12:18.17|