(±) 14-HDHA
Product Specifications
CAS Number
87042-40-8
Target
Drug Metabolite, Endogenous Metabolite
Related Pathways
Metabolism
Bioactivity
(±) 14-HDHA is a hydroxydocosahexaenoic acid, an oxidized metabolite of DHA generated intracellularly by enzymatic or non-enzymatic reactions, is one of the specific substrates of 15-PGDH and can be further oxidized to the anti-inflammatory 14-oxoDHA, and in primary alveolar macrophages, 14-HDoHE itself significantly inhibits LPS-induced IL-6 mRNA expression in primary alveolar macrophages, which may be relevant to inflammatory diseases such as asthma.
Smiles
C(\C(C/C=C\C/C=C\CC)O)=C/C=C\C/C=C\C/C=C\CCC(O)=O
Molecular Formula
C22H32O3
Molecular Weight
344.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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