12-HETE
Product Specifications
CAS Number
71030-37-0
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
12-HETE ((±) 12-HETE) is a modulator of PGE2, with both anti-thrombotic and pro-thrombotic effects, inducing PGE2 release and COX-2 expression via phospholipase A2 (sPLA2-IIA) inducers. It is also a neuroregulator activating retinal cell endothelial dysfunction in diabetic retinopathy.
Smiles
C(\C(C/C=C\CCCCC)O)=C/C=C\C/C=C\CCCC(O)=O
Molecular Formula
C20H32O3
Molecular Weight
320.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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