What is the catalog number for X-376?

The catalog number for X-376 is T3550.

What sizes are available for X-376?

X-376 is available in the following size(s): 1 mg, 2 mg, 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does X-376 come in?

X-376 is available in 8 different pack sizes.

X-376 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures X-376?

X-376 is manufactured by Molfinity.

What is the estimated delivery time for X-376?

Estimated delivery time for X-376 is approximately 10 business day(s), depending on your location.

X-376

Product Specifications

CAS Number

1365267-27-1

Target

C-Met/HGFR, ALK

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors

Purity

0.9872

Bioactivity

X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inhibits ALK kinase, ALK fusion proteins, and ALK point mutation variants. Inhibition of ALK leads to the disruption of ALK-mediated signaling and eventually inhibits tumor cell growth in ALK-expressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development.