(±) 13 (14) -EpDPA
Product Specifications
CAS Number
895127-64-7
Target
Cytochromes P450, Others
Related Pathways
Metabolism, Others
Bioactivity
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±) 13 (14) -EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 13,14-double bond of DHA. It has been detected in rat brain and spinal cord and is a preferred substrate for soluble epoxide hydrolase with a Km value of 3.2 μM. (±) 13 (14) -EpDPA demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models. (±) 13 (14) -EpDPA and other epoxy metabolites of DHA are also reported to potently inhibit angiogenesis and tumor growth in in vitro assays.
Smiles
CC\C=C/C\C=C/CC1OC1C\C=C/C\C=C/C\C=C/CCC(O)=O
Molecular Formula
C22H32O3
Molecular Weight
344.495
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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