DBRD9-A
Product Specifications
CAS Number
2170679-42-0
Target
Others|||PROTACs|||Epigenetic Reader Domain
Related Pathways
PROTAC|||Chromatin/Epigenetic|||Others
Bioactivity
Potent BRD9 degrader. Selectively binds BRD9 and elicits near complete degradation of BRD9 at nanomolar concentrations. Inhibits growth of synovial sarcoma cells in vitro and tumor progression in a synovial sarcoma xenograft mouse model.
Smiles
O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCCCCCCCNC(CN(CC4=C(OC)C=C(C=C4OC)C=5C=6C(C(=O)N(C)C5)=CN=CC6)C)=O
Molecular Formula
C42H49N7O8
Molecular Weight
779.88
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
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