α-GalCer analog 8
Product Specifications
CAS Number
922727-14-8
Target
Others
Related Pathways
Others
Bioactivity
α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 µg per animal dose, indicating a Th2 response.
Smiles
CCCCCCCCCCCCCCCCCCCCCCCCc1cn(nn1)[C@@H](CO[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@H](O)CCCCCCCCCCCCCC
Molecular Formula
C50H97N3O8
Molecular Weight
868.339
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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