(5E) -7-Oxozeaenol
Product Specifications
CAS Number
1198574-97-8
Target
Others
Related Pathways
Others
Bioactivity
(5E) -7-Oxozeaenol is a resorcylic acid lactone that has been found in the fungus MSX 63935 and has enzyme inhibitory and anticancer activities.1,2 It inhibits TGF-β-activated kinase 1 (TAK-1; IC50 = 1.3 μM) .1 (5E) -7-Oxozeaenol inhibits proliferation of MCF-7, H460, SF-268, HT-29, and MDA-MB-435 human cancer cells with IC50 values of 4.9, 1.2, 5.6, 4.4, and 5.5 μM, respectively.2
Smiles
COc1cc(O)c2c(c1)\C=C\C[C@H](O)[C@H](O)C(=O)\C=C\C[C@H](C)OC2=O
Molecular Formula
C19H22O7
Molecular Weight
362.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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