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Propargyl-PEG2-OH

Product Specifications

UNSPSC Description

Propargyl-PEG2-OH is a PEG-based PROTAC linker can be used in the synthesis of Thalidomide-O-PEG2-propargyl (HY-126458)[1]. Propargyl-PEG2-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Target Antigen

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/propargyl-peg2-oh.html

Purity

99.66

Solubility

Ethanol : ≥ 100 mg/mL

Smiles

C#CCOCCOCCO

Molecular Weight

144.17

References & Citations

[1]Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-130541/Propargyl-PEG2-OH-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-130541/Propargyl-PEG2-OH-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

7218-43-1

Available Sizes

Curated Selection

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