(E/Z) -THZ1 2HCl
Product Specifications
CAS Number
2095433-94-4
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.9951
Bioactivity
THZ1 2HCl (THZ1 Dihydrochloride) is a selective, covalent, and allosteric inhibitor of CDK7 with an IC50 of 3.2 nM. THZ1 2HCl has antiproliferative effects on a variety of cancer cell lines.
Smiles
Cl.Cl.CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1
Molecular Formula
C31H30Cl3N7O2
Molecular Weight
638.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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ATG7 (Autophagy 7S. Cerevisiae, APG7 Like, ATG7 HUMAN, hAGP7, Ubiquitin-Like Modifier-Activating Enzyme ATG7, Autophagy Related Protein 7, Autophagy-Related Protein 7, GSA 7, APG7, S. Cerevisiae, Homolog, Ubiquitin-Activating Enzyme E1-Like Protein, Autophagy-Related 7 (Yeast), APG7 Autophagy 7 Like, 1810013K23Rik, APG7 Autophagy 7-Like (S. Cerevisiae), ATG12-Activating Enzyme E1 ATG7, ATG7 Autophagy Related 7 Homolog, Atg7l, Ubiquitin Activating Enzyme E1 Like Protein, Apg 7, APG7L, DKFZp434N0735, ATG 7, APG7-Like, GSA7, ATG7 Autophagy Related 7 Homolog (S. Cerevisiae), ATG7)
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