(E/Z) -THZ1 2HCl
Product Specifications
CAS Number
2095433-94-4
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.9951
Bioactivity
THZ1 2HCl (THZ1 Dihydrochloride) is a selective, covalent, and allosteric inhibitor of CDK7 with an IC50 of 3.2 nM. THZ1 2HCl has antiproliferative effects on a variety of cancer cell lines.
Smiles
Cl.Cl.CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1
Molecular Formula
C31H30Cl3N7O2
Molecular Weight
638.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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