Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Senicapoc

Product Specifications

CAS Number

289656-45-7

Target

Potassium Channel

Related Pathways

Membrane transporter/Ion channel

Purity

0.995

Bioactivity

Senicapoc (ICA-17043) is a potent inhibitor of the Gardos channel that ameliorates RBC dehydration in the SAD mouse. It blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 ± 2 nM (CLT IC50 = 100 ± 12 nM) and inhibits RBC dehydration with an IC50 of 30 ± 20 nM. Senicapoc is used in the treatment of Sickle Cell Disease and Sickle Cell Anemia.

Smiles

NC(=O)C(c1ccccc1)(c1ccc(F)cc1)c1ccc(F)cc1

Molecular Formula

C20H15F2NO

Molecular Weight

323.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Hexokinase-2 (1-917, His-tag) Human Protein
AR09039PU-N 100 µg

Hexokinase-2 (1-917, His-tag) Human Protein

Sign In for Pricing
View Details
WFDC5 CRISPR Activation Plasmid (m)
sc-431625-ACT 20 µg

WFDC5 CRISPR Activation Plasmid (m)

Sign In for Pricing
View Details
Recombinant Human CD31/PECAM1 Protein, C-His
EHD16403 100 μg

Recombinant Human CD31/PECAM1 Protein, C-His

Sign In for Pricing
View Details
Trpv4 sgRNA CRISPR Lentivector set (Rat)
K7550001 3x 1.0 µg

Trpv4 sgRNA CRISPR Lentivector set (Rat)

Sign In for Pricing
View Details
GJC3 Antibody Blocking Peptide
orb1500992 500 µg

GJC3 Antibody Blocking Peptide

Sign In for Pricing
View Details
Biotin-Linked Polyclonal Antibody to Glutathione S Transferase Kappa 1 (GSTk1)
MBS2092874-01 0.1 mL

Biotin-Linked Polyclonal Antibody to Glutathione S Transferase Kappa 1 (GSTk1)

Sign In for Pricing
View Details