5α-Hydroxy-6-keto cholesterol
Product Specifications
CAS Number
13027-33-3
Target
Endogenous Metabolite
Related Pathways
Metabolism
Bioactivity
5α-Hydroxy-6-keto cholesterol is a β-epoxide metabolite and cholesterol derivative produced in human bronchial epithelial cells (16-HBE) exposed to ozone. It inhibits cholesterol synthesis (IC50=350 nM) and exhibits cytotoxicity.
Smiles
C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC(=O)[C@@]1(O)C[C@@H](O)CC2)[H])[H]
Molecular Formula
C27H46O3
Molecular Weight
418.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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