VU0486321
Product Specifications
CAS Number
1816301-67-3
Target
Others, GluR
Related Pathways
Neuroscience, Others
Bioactivity
VU0486321 is a potent mGlu1 PAM with moderate rat PK (CLp = 13.3. mL/min/kg, t1/2 = 54 min), good free fraction (human fu = 0.05, rat fu =0.03) and excellent CNS penetration (Kp = 1.02) .
Smiles
O=C1N(C(=O)C=2C1=C(F)C=CC2)C3=C(Cl)C=C(NC(=O)C4=C(C)C=CO4)C=C3
Molecular Formula
C20H12ClFN2O4
Molecular Weight
398.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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