3-MATIDA
Product Specifications
CAS Number
518357-51-2
Target
NMDAR, Others, GluR
Related Pathways
Neuroscience, Others
Purity
0.9996
Bioactivity
3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a) . Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM) . 3-MATIDA act as a neuroprotectant in cultured murine cortical cells and rat hippocampal slice cultures in vitro.
Smiles
C(C(O)=O)(N)C=1SC(C(O)=O)=CC1C
Molecular Formula
C8H9NO4S
Molecular Weight
215.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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