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3-MATIDA

Product Specifications

CAS Number

518357-51-2

Target

NMDAR|||Others|||GluR

Related Pathways

Neuroscience|||Others

Purity

0.9996

Bioactivity

3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 ?M, rat mGluR-1a) . Displays ? 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 ?M), NMDA and GluR (AMPA) (IC50 = 250 ?M) . 3-MATIDA act as a neuroprotectant in cultured murine cortical cells and rat hippocampal slice cultures in vitro.

Smiles

C(C(O)=O)(N)C=1SC(C(O)=O)=CC1C

Molecular Formula

C8H9NO4S

Molecular Weight

215.23

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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