Ro 67-7476
Product Specifications
CAS Number
298690-60-5
Target
GluR
Related Pathways
Neuroscience
Purity
0.9969
Bioactivity
Ro 67-7476 is a positive allosteric modulator of mGluR1, which can enhance the calcium release induced by glutamate in HEK293 cells expressing rat mGluR1a. The EC50 is 60.1 nM. It is a P-ERK1/2 agonist, and can activate ERK1/2 phosphorylation without the addition of exogenous glutamate (EC50 = 163.3 nM) .
Smiles
Cc1ccc(cc1)S(=O)(=O)N1CCC[C@H]1c1ccc(F)cc1
Molecular Formula
C17H18FNO2S
Molecular Weight
319.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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