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Vesnarinone

Product Specifications

CAS Number

81840-15-5

Target

HIV Protease, PDE

Related Pathways

Microbiology/Virology, Metabolism, Proteases/Proteasome

Purity

0.9875

Bioactivity

Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. It also suppresses cell proliferation and induces apoptosis by inducing the expression of p21, an inhibitor of cyclin-dependent kinase activity in p53-mediated cell cycle arrest.

Smiles

COc1ccc(cc1OC)C(=O)N1CCN(CC1)c1ccc2NC(=O)CCc2c1

Molecular Formula

C22H25N3O4

Molecular Weight

395.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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