Vesnarinone
Product Specifications
CAS Number
81840-15-5
Target
HIV Protease, PDE
Related Pathways
Microbiology/Virology, Metabolism, Proteases/Proteasome
Purity
0.9875
Bioactivity
Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. It also suppresses cell proliferation and induces apoptosis by inducing the expression of p21, an inhibitor of cyclin-dependent kinase activity in p53-mediated cell cycle arrest.
Smiles
COc1ccc(cc1OC)C(=O)N1CCN(CC1)c1ccc2NC(=O)CCc2c1
Molecular Formula
C22H25N3O4
Molecular Weight
395.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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