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SG3199

Product Specifications

CAS Number

1595275-71-0

Target

ADC Cytotoxin, DNA Alkylator/Crosslinker

Related Pathways

Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair

Bioactivity

SG3199 is a PBD dimer which binds in the minor groove of DNA, and forms covalent DNA interstrand cross-links in naked linear plasmid DNA. SG3199 is potently cytotoxic against a panel of human solid tumour and haematological cancer cell lines.

Smiles

[H][C@@]12CC(C)=CN1C(=O)c1cc(OC)c(OCCCCCOc3cc4N=C[C@]5([H])CC(C)=CN5C(=O)c4cc3OC)cc1N=C2

Molecular Formula

C33H36N4O6

Molecular Weight

584.66

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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