SG3199
Product Specifications
CAS Number
1595275-71-0
Target
ADC Cytotoxin, DNA Alkylator/Crosslinker
Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
Bioactivity
SG3199 is a PBD dimer which binds in the minor groove of DNA, and forms covalent DNA interstrand cross-links in naked linear plasmid DNA. SG3199 is potently cytotoxic against a panel of human solid tumour and haematological cancer cell lines.
Smiles
[H][C@@]12CC(C)=CN1C(=O)c1cc(OC)c(OCCCCCOc3cc4N=C[C@]5([H])CC(C)=CN5C(=O)c4cc3OC)cc1N=C2
Molecular Formula
C33H36N4O6
Molecular Weight
584.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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