What is the catalog number for Merestinib?

The catalog number for Merestinib is T3455.

What sizes are available for Merestinib?

Merestinib is available in the following size(s): 1 mg, 2 mg, 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 500 mg.

How many pack sizes does Merestinib come in?

Merestinib is available in 9 different pack sizes.

Is Merestinib in stock?

Merestinib is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Merestinib?

Merestinib is manufactured by Molfinity.

What is the estimated delivery time for Merestinib?

Estimated delivery time for Merestinib is approximately 10 business day(s), depending on your location.

Merestinib

Product Specifications

CAS Number

1206799-15-6

Target

ROS, ROS Kinase, FLT, c-Met/HGFR, Discoidin Domain Receptor (DDR)

Related Pathways

Angiogenesis, Immunology/Inflammation, Tyrosine Kinase/Adaptors

Purity

0.9971

Bioactivity

Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity. Merestinib electively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing the constitutively activated c-Met protein.