Praziquantel

Praziquantel is a broadly effective trematocide and cestocide, the initial effect of praziquantel on the schistosome may be an interaction of the drug with lipid constituents of the tegumental membrane. Praziquantel is used for the research of schistosomiasis[1][2].

Product Specifications

CAS Number

[55268-74-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Praziquantel.html

Purity

99.82

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

O=C1CN(C(C2CCCCC2)=O)CC3N1CCC4=C3C=CC=C4

Molecular Formula

C19H24N2O2

Molecular Weight

312.41

Precautions

H302, H315, H319, H335

References & Citations

[1]Qian Sun, et al. The cytotoxicity study of praziquantel enantiomers. Drug Des Devel Ther. 2016 Jun 24;10:2061-8.|[2]Andrews P, et al. Praziquantel: mechanisms of anti-schistosomal activity. Pharmacol Ther. 1985;29 (1) :129-56.