Redaporfin
Product Specifications
CAS Number
1224104-08-8
Target
Others, ROS, Reactive Oxygen Species
Related Pathways
Others, NF-κB, Immunology/Inflammation, Metabolism
Bioactivity
Redaporfin, also known as F-2BMet or LUZ-11, is a photosensitizer for Photodynamic Therapy (PDT) of cancer. Redaporfin showed a high efficacy in the treatment of male BALB/c mice with subcutaneously implanted colon (CT26) tumours. Vascular-PDT with 1.5 mg/kg redaporfin and a light dose of 74 J/cm2 led to the complete tumour regression in 83% of the mice.
Smiles
CNS(=O)(=O)c1ccc(F)c(c1F)-c1c2CCc(n2)c(-c2c(F)ccc(c2F)S(=O)(=O)NC)c2ccc([nH]2)c(c2CCc(n2)c(-c2c(F)ccc(c2F)S(=O)(=O)NC)c2ccc1[nH]2)-c1c(F)ccc(c1F)S(=O)(=O)NC
Molecular Formula
C48H38F8N8O8S4
Molecular Weight
1135.11
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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