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Kaempferitrin

Product Specifications

CAS Number

482-38-2

Target

Cell Cycle Arrest, Glucokinase, IGF-1R

Related Pathways

Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, Metabolism

Purity

0.9959

Bioactivity

Kaempferitrin (Lespenephryl) has antidepressant-like effect related to the serotonergic system, principally 5-HT1A. Kaempferitrin exerts cytotoxic and antitumor effects against HeLa cells. Kaempferitrin stimulates glucose-metabolizing enzymes, promotes glucose homeostasis. Kaempferitrin exerts immunostimulatory effects on immune responses mediated by splenocytes, macrophages, PBMC and NK cells. Kaempferitrin induces cytotoxic effects to include: cell cycle arrest in G1 phase and apoptosis via the intrinsic pathway in a caspase-dependent pathway.

Smiles

C[C@@H]1O[C@@H](Oc2cc(O)c3c(c2)oc(-c2ccc(O)cc2)c(O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)c3=O)[C@H](O)[C@H](O)[C@H]1O

Molecular Formula

C27H30O14

Molecular Weight

578.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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