Kaempferitrin
Product Specifications
CAS Number
482-38-2
Target
Cell Cycle Arrest, Glucokinase, IGF-1R
Related Pathways
Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, Metabolism
Purity
0.9959
Bioactivity
Kaempferitrin (Lespenephryl) has antidepressant-like effect related to the serotonergic system, principally 5-HT1A. Kaempferitrin exerts cytotoxic and antitumor effects against HeLa cells. Kaempferitrin stimulates glucose-metabolizing enzymes, promotes glucose homeostasis. Kaempferitrin exerts immunostimulatory effects on immune responses mediated by splenocytes, macrophages, PBMC and NK cells. Kaempferitrin induces cytotoxic effects to include: cell cycle arrest in G1 phase and apoptosis via the intrinsic pathway in a caspase-dependent pathway.
Smiles
C[C@@H]1O[C@@H](Oc2cc(O)c3c(c2)oc(-c2ccc(O)cc2)c(O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)c3=O)[C@H](O)[C@H](O)[C@H]1O
Molecular Formula
C27H30O14
Molecular Weight
578.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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