NVS-SM2
Product Specifications
CAS Number
1562333-92-9
Target
Others|||DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Others
Bioactivity
NVS-SM2 is an effective small molecule splicing enhancer of SMN2 with oral activity. NVS-SM2 showed increased exon 7 inclusion and upregulated SMN protein expression in SMA fibroblasts and SMN cells ?7 5025 mouse myoblasts.
Smiles
CN(C1CC(C)(C)NC(C)(C)C1)c1ccc(nn1)-c1ccc(cc1O)-c1cn[nH]c1
Molecular Formula
C23H30N6O
Molecular Weight
406.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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034743-ML750 100 µL
DNMT2, ID (A198) (tRNA (cytosine-5-) -methyltransferase, DNA (cytosine-5) -methyltransferase-like protein 2, Dnmt2, DNA methyltransferase homolog HsaIIP, DNA MTase homolog HsaIIP, M.HsaIIP, PuMet, TRDMT1, DNMT2, ) (MaxLight 750) discontinued
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