NVS-SM2

Product Specifications

CAS Number

1562333-92-9

Target

Others|||DNA/RNA Synthesis

Related Pathways

DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Others

Bioactivity

NVS-SM2 is an effective small molecule splicing enhancer of SMN2 with oral activity. NVS-SM2 showed increased exon 7 inclusion and upregulated SMN protein expression in SMA fibroblasts and SMN cells ?7 5025 mouse myoblasts.

Smiles

CN(C1CC(C)(C)NC(C)(C)C1)c1ccc(nn1)-c1ccc(cc1O)-c1cn[nH]c1

Molecular Formula

C23H30N6O

Molecular Weight

406.52

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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