What is the catalog number for Ombuoside?

The catalog number for Ombuoside is HY-N3138.

What sizes are available for Ombuoside?

Ombuoside is available in the following size(s): 5 mg.

Is Ombuoside in stock?

Ombuoside is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ombuoside?

Ombuoside is manufactured by QuantiMol.

What is the estimated delivery time for Ombuoside?

Estimated delivery time for Ombuoside is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ombuoside?

The safety data sheet for Ombuoside is available here: http://file.medchemexpress.com/batch_PDF/HY-N3138/Ombuoside-SDS-MedChemExpress.pdf.

Ombuoside

Ombuoside has antioxidant properties, inhibiting ROS production and apoptosis. Ombuoside exerts neuroprotective effects through the ERK-JNK-caspase-3 system. Ombuoside promotes Dopamine biosynthesis through TH and CREB activation. Ombuoside exhibits antimicrobial activity against several Gram-positive and Gram-negative bacteria, as well as Candida albicans[1][2][3][4][5]

Product Specifications

CAS Number

20188-85-6

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Bacterial; Caspase; ERK; Fungal; JNK; Reactive Oxygen Species (ROS) ; SOD

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ombuoside.html

Purity

99.68

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1C(O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]([C@H]2O)CO[C@H](O[C@H]3C)[C@@H]([C@@H]([C@H]3O)O)O)=C(C(C=C4)=CC(O)=C4OC)OC5=CC(OC)=CC(O)=C15

Molecular Formula

C29H34O16

Molecular Weight

638.57

Precautions

H302, H315, H319, H335

References & Citations

[1]Wu X, et al. New application of ombuoside in protecting auditory cells from cisplatin-induced ototoxicity via the apoptosis pathway. Heliyon. 2024 Oct 9;10 (20) :e39166. |[2]Davaasambuu U, et al.Ombuoside from Gynostemma pentaphyllum Protects PC12 Cells from L-DOPA-Induced Neurotoxicity. Planta Med. 2018 Sep;84 (14) :1007-1012. |[3]Uchralsaikhan Davaasambuu1, et al. Ameliorative Effects of Ombuoside on Dopamine Biosynthesis in PC12 Cells. Natural Product Sciences 2018;24 (2) :99-102.|[4]Amaro-Luis JM, et al. Isolation, identification and antimicrobial activity of ombuoside from Stevia triflora. Ann Pharm Fr. 1997;55 (6) :262-8. |[5]Abreu PM, et al. Antioxidant compounds from Ebenus pinnata. Fitoterapia. 2007 Jan;78 (1) :32-4.