Motexafin gadolinium
Product Specifications
CAS Number
246252-06-2
Target
Others
Related Pathways
Others
Bioactivity
Motexafin gadolinium, also known as PCI 0120, is a synthetic metallotexaphyrin with radiosensitizing and chemosensitizing properties. Motexafin gadolinium accumulates in tumor cells preferentially due to their increased rates of metabolism, generating reactive oxygen species (ROS) intracellularly and lowering the tumor cell apoptotic threshold to ionizing radiation and chemotherapy.
Smiles
CCC1=C2[N-]3[Gd+3]456([N](c7c([N]4=CC4=[N]5C(=CC3=C1CC)C(CCCO)=C4C)cc(c(c7)OCCOCCOCCOC)OCCOCCOCCOC)=CC1=[N]6C(=C2)C(CCCO)=C1C)([O-]C(=O)C)[O-]C(=O)C |c:10,12,15,18,27,57,59,62,69,t:2,^1:4,6,9,12,54|
Molecular Formula
C52H72GdN5O14
Molecular Weight
1148.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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