LCB 03-0110 dihydrochloride
Product Specifications
CAS Number
1962928-28-4
Target
Src
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.999
Bioactivity
LCB 03-0110 Dihydrochloride is a potent inhibitor of the c-Src kinase (IC50 = 1.3 nM) and tyrosine kinases in the BTK and SYK family, as well as in the DDR2 family. It inhibits LPS-induced activation of macrophages and TGF-β1-induced activation of fibroblasts in vitro, inhibits activation of macrophages and fibroblasts, and inhibits scarring in wound healing models.
Smiles
Cl.Cl.Oc1cccc(Nc2ccnc3cc(sc23)-c2cccc(CN3CCOCC3)c2)c1
Molecular Formula
C24H25Cl2N3O2S
Molecular Weight
490.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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