Niraparib
Product Specifications
CAS Number
1038915-60-4
Target
PARP, Apoptosis
Related Pathways
Apoptosis, DNA Damage/DNA Repair, Chromatin/Epigenetic
Purity
0.9991
Bioactivity
Niraparib (MK-4827) is a PARP inhibitor that selectively targets PARP1 and PARP2 (IC50=3.8/2.1 nM), exhibiting antitumor activity, inhibiting DNA damage repair, and inducing apoptosis.
Smiles
C(N)(=O)C=1C=2C(=CN(N2)C3=CC=C(C=C3)[C@@H]4CCCNC4)C=CC1
Molecular Formula
C19H20N4O
Molecular Weight
320.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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