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NLRP3-IN-2

Product Specifications

CAS Number

16673-34-0

Target

NOD, NOD-like Receptor (NLR)

Related Pathways

Immunology/Inflammation, NF-κB

Purity

0.9898

Bioactivity

NLRP3-IN-2 (5-Chloro-N- (p-sulfamoylphenethyl) -o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting infarct size after myocardial ischemia/reperfusion in mice and has no effect on metabolism.

Smiles

COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(N)(=O)=O

Molecular Formula

C16H17ClN2O4S

Molecular Weight

368.84

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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