NLRP3-IN-2
Product Specifications
CAS Number
16673-34-0
Target
NOD, NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation, NF-κB
Purity
0.9898
Bioactivity
NLRP3-IN-2 (5-Chloro-N- (p-sulfamoylphenethyl) -o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting infarct size after myocardial ischemia/reperfusion in mice and has no effect on metabolism.
Smiles
COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(N)(=O)=O
Molecular Formula
C16H17ClN2O4S
Molecular Weight
368.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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