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AMG-337

Product Specifications

CAS Number

1173699-31-4

Target

C-Met/HGFR|||Caspase|||Apoptosis

Related Pathways

Proteases/Proteasome|||Tyrosine Kinase/Adaptors|||Apoptosis

Purity

0.999

Bioactivity

AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337 (AMG337) inhibits MET kinase activity (IC50: < 5 nM) .

Smiles

COCCOc1cnc2ccn([C@H](C)c3nnc4c(F)cc(cn34)-c3cnn(C)c3)c(=O)c2c1

Molecular Formula

C23H22FN7O3

Molecular Weight

463.46

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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