GSK172981
Product Specifications
CAS Number
1133705-99-3
Target
Others
Related Pathways
Others
Bioactivity
GSK172981 is a non-peptide tachykinin NK3 receptor antagonist with a high affinity for the recombinant human (PK (I) value 7.7) and native guinea pig (PK (I) value 7.8) tachykinin NK3 receptor. In vitro, the functional evaluation showed that GSK172981 was a competitive antagonist for the cloned human tachykinin NK (3) receptor (PA (2) =7.2) . GSK172981 may be used to treat schizophrenia.
Smiles
C(N[C@@H]([C@@H]1CC1)C2=CC=CC=C2)(=O)C=3C4=C(N=C(C3N)C5=CC(F)=CC=C5)C=CC=C4
Molecular Formula
C26H22FN3O
Molecular Weight
411.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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