GRC-17536
Product Specifications
CAS Number
1649479-05-9
Target
Others
Related Pathways
Others
Bioactivity
GRC-17536 is an orally available, potent, and selective transient receptor potential anchor protein 1 (TRPA1) inhibitor that has been shown to be highly effective in the treatment of inflammation and neuropathic pain in animal models. The selectivity of GRC-17536 is more than 1000 times higher than that of other TRPs, numerous GPCRs, enzymes, and other ion channels.
Smiles
Cn(c(scc1CC([N-]c2scc(c3c(F)c(C(F)(F)F)c(F)cc3)n2)=O)c1c(=O)n4C)c4=O.[K+]
Molecular Formula
C20H12F5KN4O3S2
Molecular Weight
554.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
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