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GNF-1331

Product Specifications

CAS Number

603101-22-0

Target

Others, Porcupine, Wnt/beta-catenin

Related Pathways

Others, Cytoskeletal Signaling, Stem Cells

Bioactivity

GNF-1331 is a potent, selective, and orally bioavailable porcupine inhibitor (IC50 = 12 nM) . Blocking abnormal Wnt signaling is an attractive treatment for a variety of cancers.

Smiles

C(CC)N1C(=NN=C1SCC(NC=2SC=3C(N2)=CC=C(OC)C3)=O)C=4C=CN=CC4

Molecular Formula

C20H20N6O2S2

Molecular Weight

440.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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