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3-Hydroxyoctanoic acid

3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly (3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.

Product Specifications

CAS Number

[14292-27-4]

UNSPSC

12352200

Hazard Statement

H315, H319

Target

Endogenous Metabolite

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/3-hydroxyoctanoic-acid.html

Purity

98.0

Solubility

DMSO : 42.5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 10 mg/mL (ultrasonic)

Smiles

CCCCCC(O)CC(O)=O

Molecular Formula

C8H16O3

Molecular Weight

160.21

Precautions

H315, H319

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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